TransCode Therapeutics, Inc.?s co-founder and Chief Executive Officer, Michael Dudley, announced his retirement. He will resign as director of the company effective January 13, 2024. TransCode?s Board of Directors thanks Mr. Dudley for his many contributions to the company since its formation in 2016.

Under his leadership, TransCode in-licensed its foundational technology, developed seven distinct product categories showcasing the potential of the company?s TTX delivery platform, completed its initial public offering in July 2021, initiated its first-in-human Phase 0 clinical trial with TTX-MC138, and dosed its first patient in that trial. In addition, Mr. Dudley hired TransCode?s executive management team, which enabled the company to reach its many milestones. In connection with the restructuring, TransCode?s Board also elevated Dr. Zdravka Medarova, PhD, currently Chief Technology Officer, to the role of Chief Scientific Officer.

Dr. Medarova is a scientific co-founder of the company and has been the leading scientific force at the company advancing TransCode?s science. Dr. Medarova is expected to become increasingly active in partnership and collaboration discussions as well as overseeing TransCode?s science and intellectual property activities. Dr. Philippe Calais, PharmD, PhD, currently Chairman of the Board of Directors, will assume the position of Executive Chairman.

Dr. Calais is a senior executive with extensive global management experience. He has 23 years of experience as a CEO and board member of public and private biotechnology companies in North America and Europe. His experience includes initial public offerings and other equity financings, investor relations, mergers, acquisitions, asset sales and complex international company restructurings.

He also has deep experience managing across all functions of the drug discovery and development value chain, including 14 years in big pharma, with increasing responsibilities up to corporate executive heading up the leading franchise at Hoffmann-La Roche in the late 1990s.