Mithra Pharmaceuticals SA announced they have signed a binding supply agreement for the active pharmaceutical ingredient (API) for the combined oral contraceptive Estelle and Donesta, a novel product candidate for the treatment of post-menopausal symptoms. The agreement specifies that Gedeon Richter will manufacture and supply the Estetrol (E4) native estrogen for Mithra?s Estelle® and Donesta®. Gedeon Richter will manufacture and supply Estetrol (E4) for production of Estelle®, Donesta® Strengthens Mithra?ssupplychainwith commercially attractive source for Estetrol .