Item 1.01 Entry into a Material Definitive Agreement.

On April 3, 2023, Histogen Inc. (the "Company") entered into an Exclusive License Agreement (the "Agreement") with Johns Hopkins University ("Johns Hopkins"), pursuant to which Johns Hopkins granted the Company an exclusive license to certain intellectual property associated with the use of emricasan for the treatment of disease in humans resulting from viral or bacterial infections (including but not limited to, MRSA, VRSA, and SARS-CoV-2). In exchange, the Company agreed to pay Johns Hopkins an upfront license fee, reimbursement of certain patent costs, milestones, and royalties. The Agreement contains customary provisions on, among other things, termination, indemnification and patent prosecution and maintenance of the licensed intellectual property portfolio.

The foregoing description of the Agreement does not purport to be complete and is qualified in its entirety by reference to the text of the Agreement, which will be filed with the Company's next Quarterly Report on Form 10-Q.




Item 8.01. Other Events.


On April 3, 2023, the Company issued a press release announcing the transaction with Johns Hopkins. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits

Exhibit
Number    Exhibits
   99.1     Press Release, dated April 3, 2023
   104    Cover Page Interactive Data File (embedded within the Inline XBRL document)




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