- Companies to focus on cardiovascular, metabolic, and other indications
- OliX will receive initial upfront payment of
$6.5 million with up to$450 million plus royalties
Through this agreement, OliX will use its GalNAc-asiRNA platform technology to discover lead compounds and secure development candidates for targets in cardiovascular, metabolic, and other diseases associated with the liver. Hansoh will have exclusive commercial rights to these therapeutics in
“We are thrilled to partner with OliX Pharmaceuticals, a leader in siRNA development with an established clinical stage portfolio, and look forward to utilizing their technology platform in our development process,” said
“We are extremely excited to partner with one of the largest biopharmaceutical entities in Greater China,” said
Asymmetric small interfering RNA
Asymmetric small interfering RNA (asiRNA) represents the next generation of RNAi therapeutics through efficient gene regulation. Compared to existing siRNA therapeutics, OliX Pharmaceuticals’ asiRNA shows comparable gene silencing and significantly reduced siRNA-mediated side effects such as off-target gene silencing and immune stimulation.
About
Founded in 1995, Hansoh has fully integrated research and development, manufacturing, and commercial capabilities, supporting leading positions across a broad range of therapeutic areas, including oncology, central nervous system (CNS) disorders, infectious diseases, cardiovascular diseases, diabetes, and autoimmune diseases, among others. With the support of over 1,600 highly skilled R&D professionals, Hansoh has successfully developed multiple internally discovered drug candidates into NMPA-approved innovative medicines, including aumolertinib (阿美乐®), a third-generation EGFR inhibitor for the treatment of NSCLC with EGFR mutations; flumatinib (昕福®), a second-generation BCR-ABL inhibitor for frontline treatment of chronic myeloid leukemia (CML); PEG-loxenatide (孚来 美®), the first once-weekly long-acting GLP-1 analogue discovered and developed in
For more information, please visit www.hspharm.com
About OliX Pharmaceuticals
OliX Pharmaceuticals is a clinical stage pharmaceutical company developing therapeutics against a variety of disorders by down-regulating expression of disease-causing genes based on its own proprietary RNAi technology. The Company’s core RNAi platform, asymmetric siRNA (asiRNA), is a unique gene silencing technology based on RNA interference (RNAi), which is considered the most efficient gene silencing technology. Utilizing this proprietary asiRNA technology, OliX has developed cell penetrating asiRNA (cp-asiRNA), a therapeutic RNAi platform to effectively target diseases locally, such as hypertrophic scarring, dry and wet age-related macular degeneration (AMD), subretinal fibrosis, idiopathic pulmonary fibrosis (IPF), and neuropathic pain. OliX has also developed another therapeutic RNAi platform, GalNAc-asiRNA, to target a variety of liver diseases.
Learn more: https://www.olixpharma.com/eng/main/main.php
OliX Media Contact:
ICR Westwicke PR
Phone: +1.475.395.5375
jon.yu@westwicke.com
Source: OliX Pharmaceuticals;
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