Asarina Pharma has completed the recruitment of patients to its Phase IIa clinical study in Tourette syndrome with a total of 28 patients enrolled and the last patient randomized on October 14. The dropout rate in the study remains unexpectedly low. Topline results are expected at the end of first quarter of 2023.

The study compound, Sepranolone, is an endogenous neurosteroid, an entirely new treatment modality for Tourette. It has demonstrated a strong safety prolife in multiple previous clinical studies, and reduced tics without inducing any motor side effects in previous preclinical studies. Enrollment of adult patients started at the Bispebjerg University Hospital in Copenhagen in February 2022, while teenage patients have been enrolled at the Danish National Center for Tourette at Herlev University Hospital since summer 2022.

Until now, a total of 13 patients have completed the study. Last-patient-last-visit remains scheduled for January 2023 with topline results expected at the end of March 2023.