Item 7.01 Regulation FD Disclosure

On April 3, 2023, MainStreet Bancshares, Inc. (the "Company") announced that it will conduct a virtual webcast and quarterly earnings conference call on Monday, April 17, 2023, at 2:00 p.m. Eastern Time during which the Company will discuss first quarter results as well as provide an update on recent activities. Investors that are interested in attending the virtual webcast should contact Hattie Lester by email at hlester@mstreetbank.com or by phone at (571)-375-1364.

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