M3, Inc.

Presentation Material

April 2024

Copyright © 2024 M3, Inc. All rights reserved.

The following presentation contains forecasts, future plans, management targets and other forward-looking projections relating to M3, Inc. and/or its group. These statements are drawn from assumptions of future events based on data currently available to us, and there exist possibilities that such assumptions are objectively incorrect and/or may produce differing actual results from those mentioned in the statements.

Furthermore, information and data other than those concerning the Company and its subsidiaries/affiliates are quoted from public information, and the Company has not verified and will not warrant its accuracy or dependency.

M3, Inc.

Copyright © 2024 M3, Inc. All rights reserved.

1

FY2023 Consolidated Results

Unit: JPY MM

FY2022

Sales

230,818

Operating

71,983

Profit

Pre-tax

74,318

Profit

Net Profit

51,983

FY2023

238,883

64,381

68,840

48,549

YoY

+3%

-11%

-7%

-7%

YoY growth in business excluding COVID related revenues, sales +11%

Excluding the impact of impairment losses, OP was -2% YOY

Regular business has achieved double-digit growth in sales, while OP was down due to a slowdown in pharmaceutical marketing support, caused by a drop of temporarily surged demand in the COVID period and budget compression in some pharmaceutical companies, and a slowdown in US clinical trial business, in addition to the recognition of

impairment losses Copyright © 2024 M3, Inc. All rights reserved.

2

Consolidated Sales Trends and COVID Impact

Unit: JPY MM

238,883

COVID related

230,818

(clinical trials,

208,159

24,300

10,400

vaccination support,

promotion of

169,198

24,800

+11%

therapeutic drugs and

vaccines, etc.)

Regular

businesses

FY2020

FY2021

FY2022

FY2023

COVID-related revenues saw a decrease of approximately 14 billion yen for FY2023, significantly impacting profits. For FY2024, COVID-related revenues are expected to harm sales of around 7 billion yen

*FY22 Actuals: Q1 ~8.1 Bn, Q2 ~6.4 Bn, Q3 ~6.2 Bn, Q4 ~3.5 Bn

FY23 Actuals: Q1 ~3.0 Bn, Q2 ~2.7 Bn, Q3 ~2.7 Bn, Q4 ~2.0 Bn

Copyright © 2024 M3, Inc. All rights reserved.

3

FY2023 Consolidated Results by Segment

Unit: JPY MM

Medical

Platform

Evidence

Domestic

Solution

Career

Solution

Site

Solution

Emerging

Businesses

Overseas

* M3EM3 Education, Inc.

Pharma marketing: The year-

FY2022

FY2023

YoY

end budget spending for Q4

was also limited, but the

fundamental DX is still

Sales

93,098

93,414

+0%

progressing

Other businesses such as DX

Profit

41,147

38,626

-6%

of the clinical scene showed

steady growth

Sales

27,157

26,700

-2%

Order backlog: 29.1 Bn

Profit

7,662

6,698

-13%

Sales +3% excluding COVID

Short-term negative impact

Sales

14,538

16,642

+14%

due to completion of major

projects

Profit

4,644

4,781

+3%

Sales +22% excluding COVID

Sales

35,295

33,025

-6%

Profit

3,745

3,735

-0%

Sales +33% excluding COVID

Recorded an impairment loss

Sales

3,284

2,633

-20%

for M3E*, due to shrinking

Profit

945

-290

-

market for graduated dental

students

Sales

62,095

69,868

+13%

Sales +20% excluding COVID

Impairment loss in US clinical

Profit

16,990

11,695

-31%

trial business

Europe and APAC region

steady

Copyright © 2024 M3, Inc. All rights reserved.

4

FY2023 Forecast vs. Actuals

Initial outlook

Medical Platform

Evidence Solutions

Career Solutions

Site Solutions

Overseas

Other / Adjustments

FY2023 Act.

Sales

Operating profit

250.0 bn

75.0 bn

238.9 bn

64.4 bn

Missed targets mainly due to Overseas and Medical Platform segments, especially Overseas, where profit shortfalls increased due to impairment loss

Copyright © 2024 M3, Inc. All rights reserved.

5

Background of Impairment loss and Recovery Plan for US Clinical Trial Business

Sales trend in US clinical trial business

Management base and structure

renewal:

(JPY Bn)

9.3

COVID-related Regular business

Impairment loss due to the decline

in COVID-related revenues, but

cumulative returns since

acquisition have been almost

7.7

6.8

4.6

2.9

FY19 FY20 FY21 FY22 FY23 FY24 FY25

realized… Accelerate efforts for

future recovery

Improvement of cost structure:

Reviewed and downsized the

organization that had expanded in

response to the surge in demand

during the COVID period, to make

the organization more muscular

(already implemented in April)

Strengthen sales and patient

recruiting functions:

Aggressively increase the number

of sales personnel and strengthen

initiatives for further growth

Copyright © 2024 M3, Inc. All rights reserved.

6

Sales Outlook for FY2024

Unit: JPY MM Percentage of COVID-

related revenues to be

significantly reduced;

growth expected to

come from growth of

270,500

regular businesses

3,000

Growth rate

Regular

businesses only Overall

COVID related

(clinical trials,

238,883

vaccination support,

promotion of

10,400

therapeutic drugs and

vaccines, etc.)

+17%

+13%

17%

Regular

businesses

FY2023 FY2024E*

13% 11%

FY2022 FY2023 FY2024E*

Driving sales growth, mainly in the Medical Platform and Overseas Segments

* The median of the range of FY2024 Forecasts (268,000273,000 million yen)

Copyright © 2024 M3, Inc. All rights reserved.

7

M3's Triple Growth Engine + CSV

1. Ecosystem

Expansion

(Sagrada Familia)

Regions (12 areas)

10

11

M P

Businesses (30

CS SS ES

- 50)

Others

2. Individual Business Development

Regions (12 areas)

10

11

M P

Businesses (30

CS SS ES

- 50)

Others

3. Ecosystem Synergy Creation

Regions (12 areas)

10

11

M P

Businesses (30

CS SS ES

- 50)

Others

  • Continuous new

business entries

Pharma marketing

Cross-cell synergy

/ Clinical Scene DX

maximization

4. Social Impact Creation → CSV

Copyright © 2024 M3, Inc. All rights reserved.

8

Growth Engine 1 Ecosystem Expansion (Sagrada Familia)

Businesses (30 - 50)

Others CS SS ESM P

Regions (12 areas)

10

11

Regions (12 areas)

10

11

M P

Businesses (30 -

CS SS ES

50)

Others

Regions (12 areas)

10

11

M P

Businesses (30 -

CS SS ES

50)

Others

4. Social Impact Creation → CSV

Copyright © 2024 M3, Inc. All rights reserved.

9

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Disclaimer

M3 Inc. published this content on 26 April 2024 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 26 April 2024 14:25:02 UTC.