Three-part report investigates rapid pipeline growth, partnerships, clinical trials, and patient access challenges in cancer treatment
CAR T (Chimeric Antigen Receptor T-cell) therapy represents a revolutionary approach to cancer treatment, harnessing the power of the body's immune system to target and destroy cancer cells. As this groundbreaking treatment gains traction in the pharmaceutical sphere, the BioWorld special report provides valuable insights into its present state and future potential. The report, authored by
- Part One:
China's investigator trials accelerate competitive CAR T development
The exponential growth ofChina's CAR T market is projected to soar from$72 million in 2022 to an impressive$342 million over the next decade. With over 400 CAR T therapies currently in the pipeline, fueled by strategic collaborations between multinational pharma giants and local biotechs, this segment promises unprecedented opportunities for growth and innovation. - Part Two: CAR T pipelines bloom to treat world's largest cancer population
As ofJan. 31, 2024 , there were more than 300 CAR T trials registered inChina , surpassing theU.S. and becoming the country with the most CAR T therapy clinical trials. Among them, CD19 is the most frequently studied target. The rapid evolution of CAR T-cell therapies inChina has escalated over the past decade from the start of the first clinical trials in 2013 to the country becoming an established host for CAR T-cell-related trials by 2017. - Part Three:
China grapples with providing access to CAR T therapies
The process of manufacturing autologous T-cell therapies is technically challenging when compared with other oncology drugs, making the overall cost of developing CAR T therapies significantly higher. A challenging reimbursement environment for drugs inChina also means that most patients will have to pay out of pocket to access CAR T therapies. Taken together, complex logistics – production, manufacturing and supply chain – and complicated administration requirements are key bottlenecks that inflate the input costs involved in developing these specialized treatment options.
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