Century Sage Scientific Holdings Limited announced the following changes with effect from 29 September 2021: Mr. Leung resigned as an executive Director, a member of the Remuneration Committee and a member of the Investment Committee; Mr. Geng resigned as an executive Director and a member of the Investment Committee; Mr. Hung resigned as an independent non-executive Director, the chairman of the Audit Committee, a member of the Remuneration Committee and a member of the Nomination Committee; Dr. Ng resigned as an independent non-executive Director, the chairman of the Remuneration Committee, a member of the Audit Committee and a member of the Nomination Committee; and Mr. Mak resigned as an independent non-executive Director, a member of the Audit Committee and a member of the Remuneration Committee. The Board announced the appointment of the following new Directors with effect from 29 September 2021: Mr. Li has been appointed as an executive Director and the chairman of the Nomination Committee; Ms. Zhao has been appointed as an executive Director, a member of the Remuneration Committee and a member of the Investment Committee; Mr. Cui has been appointed as an independent non-executive Director, a member of the Audit Committee, a member of the Remuneration Committee and a member of the Nomination Committee; Mr. Ma has been appointed as an independent non-executive Director, a member of the Audit Committee, the chairman of the Remuneration Committee, a member of the Nomination Committee and a member of the Investment Committee; and Dr. Yu has been appointed as an independent non-executive Director and the chairman of the Audit Committee. The Board announces that, with effect from 29 September 2021, Mr. Lo has resigned as a member of the Remuneration Committee and the chairman of the Nomination Committee. Following Mr. Lo's resignation in the aforementioned positions, the above resignations of the Resigning Directors and appointment of the Newly Appointed Directors: the Audit Committee comprises three independent non-executive Directors, namely Mr. Cui, Mr. Ma and Dr. Yu, of whom Dr. Yu is the chairman; the Remuneration Committee comprises two independent non-executive Directors and one executive Director, namely Ms. Zhao, Mr. Cui and Mr. Ma, of whom Mr. Ma is the chairman; the Nomination Committee comprises two independent non-executive Directors and one executive Director, namely Mr. Li, Mr. Cui and Mr. Ma, of whom Mr. Li is the chairman; and the Investment Committee comprises one independent non-executive Director and two executive Directors, namely Mr. Lo, Ms. Zhao and Mr. Ma, of whom Mr. Lo is the chairman.